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MOTS-c
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mots-c

99.418% HPLC
Mitochondrial peptide

MOTS-c (Mitochondrial Open-reading-frame of the Twelve-S rRNA type-c) is a synthetic 16-amino-acid peptide whose sequence is encoded within the mitochondrial 12S rRNA gene region rather than nuclear DNA, placing it among the class of mitochondrial-derived peptides. In published preclinical and cell-based literature it has been investigated for its role in mitochondrial metabolism, cellular energy homeostasis, and metabolic-stress signaling, and research in animal models suggests it may participate in glucose-utilization pathways. Supplied lyophilized at ≥99% HPLC purity with a per-lot Certificate of Analysis. For laboratory and research use only — not for human or animal consumption. ROEHN makes no claims regarding its effects.

1
Lot MOT10-032026-199.418% purity by HPLC · assayed Mar 7, 2026Verify →
Free cold-chain shipping over $150 · independent LC-MS/MS testing · signed COA
RUO — For research use only. Not for human or animal consumption.

A mitochondrial-derived hexadecapeptide investigated in METABOLIC-REGULATION research.

Compound
MOTS-c (Mitochondrial-derived peptide)
CAS number
1627580-64-6
Molecular formula
C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular weight
2174.62 g/mol
Sequence
Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR)
PubChem CID
146675088
Purity
≥99% by reverse-phase HPLC
Identity
Confirmed by mass spectrometry (ESI-MS)
Form
Lyophilized powder
Testing
Independent HPLC-UV + LC-MS/MS — Freedom Diagnostics
Research use
Laboratory research only — not for human or animal consumption
Made with
mots-c
lyophilized
Application
Reconstitute with bacteriostatic water per your research protocol.
Members

Laboratory handling

Reconstitution, storage & aseptic handling guidance for MOTS-c — reagent preparation notes for the lab bench.

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Assayed results — lot MOT10-032026-1
99.418%
Purity by HPLC, as assayed by Freedom Diagnostics
10.29 mg
Net peptide content recovered per vial
Pass
Bacterial endotoxin verdict — USP <85>
Mar 7, 2026
Date assayed · accession 2603060201
Figures are this lot's own assayed results, reproduced from the signed certificate as Freedom Diagnostics reported them. Analytical results only — they describe the material, not any physiological outcome. Research use only.

verified, not promised.

Enter the lot code from your roehn vial to pull its Certificate of Analysis: independent purity and identity results, published exactly as the lab reported them. Lots still in testing say so. Research use only.

View lot MOT10-032026-1 certificate →

customer reviews

4.5
average from 2 reviews

Ratings are 1–5. Reviews appear as written, after moderation for spam and off-topic content. They describe ordering, packaging and service — not any physiological outcome.

Great customer service

Great customer service. Impressive packaging and good quality.

Lily BrownUSJun 2, 2026
Quick, with great follow-up

Received my purchases quickly and appreciated the follow-up emails. Have enjoyed the research experience.

Tammy LamonsUSDec 20, 2025