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Semaglutide
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semaglutide

99.913% HPLC
GLP-1 research

Semaglutide is a synthetic 31-amino-acid peptide — an acylated analog of human glucagon-like peptide-1 (GLP-1) in which the position-2 residue is substituted with 2-aminoisobutyric acid (Aib) and a C18 fatty-diacid chain is conjugated to a lysine side chain through a γ-glutamate and short PEG spacer. Classed as a GLP-1 receptor agonist, it has been investigated in published preclinical and clinical literature for its role in glucose-regulation and metabolic research. Supplied lyophilized at ≥99% HPLC purity with a per-lot Certificate of Analysis. For laboratory and research use only — not for human or animal consumption. ROEHN makes no claims regarding its effects.

Strength
1
Lot GS05-032026-199.913% purity by HPLC · assayed Mar 21, 2026Verify →
Free cold-chain shipping over $150 · independent LC-MS/MS testing · signed COA
RUO — For research use only. Not for human or animal consumption.

A GLP-1 analog investigated in METABOLIC-REGULATION research.

Compound
Semaglutide
CAS number
910463-68-2
Molecular formula
C₁₈₇H₂₉₁N₄₅O₅₉
Molecular weight
4113.6 g/mol (average)
Sequence
31-mer: His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; Lys²⁰ acylated with a C18 diacid via γ-Glu/PEG spacer
PubChem CID
56843331
Purity
≥99% by reverse-phase HPLC
Identity
Confirmed by mass spectrometry (ESI-MS)
Form
Lyophilized powder
Testing
Independent HPLC-UV + LC-MS/MS — Freedom Diagnostics
Research use
Laboratory research only — not for human or animal consumption
Made with
semaglutide
lyophilized
Application
Reconstitute with bacteriostatic water per your research protocol.
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Laboratory handling

Reconstitution, storage & aseptic handling guidance for Semaglutide — reagent preparation notes for the lab bench.

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Assayed results — lot GS05-032026-1
99.913%
Purity by HPLC, as assayed by Freedom Diagnostics
5.87 mg
Net peptide content recovered per vial
Pass
Bacterial endotoxin verdict — USP <85>
Mar 21, 2026
Date assayed · accession 2603190353
Figures are this lot's own assayed results, reproduced from the signed certificate as Freedom Diagnostics reported them. Analytical results only — they describe the material, not any physiological outcome. Research use only.

verified, not promised.

Enter the lot code from your roehn vial to pull its Certificate of Analysis: independent purity and identity results, published exactly as the lab reported them. Lots still in testing say so. Research use only.

View lot GS05-032026-1 certificate →