cognitive
Research Use OnlySelank / Semax
A research formulation of Selank, a synthetic heptapeptide derived from tuftsin, and Semax, a synthetic peptide fragment of ACTH(4-10). Examined in pre-clinical literature for their respective action on BDNF expression and monoaminergic signaling pathways. Sold for laboratory research and identification purposes only. Not for human consumption.
Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
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Certificate of Analysis
Certificate of Analysis
COA documentation is being prepared for this product.
Contact research@roehn.co for batch-specific testing data.
Research Overview
About Selank / Semax
Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg), extended with three additional residues (Pro-Gly-Pro) to confer CNS bioactivity and resistance to enzymatic degradation. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, it has been investigated for anxiolytic properties mediated through GABAergic system modulation, serotonin metabolism regulation, and BDNF upregulation in limbic structures.
Semax is a synthetic heptapeptide based on the ACTH(4-10) fragment, engineered for enhanced metabolic stability and CNS penetration. Research has focused on its stimulation of BDNF and NGF synthesis in cortical and hippocampal neurons, its modulation of dopaminergic and serotonergic neurotransmission, and neuroprotective effects documented in ischemia models.
The combination targets complementary cognitive dimensions — Selank's anxiolytic, stress-buffering profile alongside Semax's pro-cognitive, attention-enhancing properties — offering a dual approach to central nervous system research. ROEHN supplies this blend at 99% HPLC-verified purity (each component), typically administered intranasally to leverage direct olfactory and trigeminal nerve pathways into the CNS.
